Malignant struma ovarii causing thyrotoxicosis

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Case report: Malignant struma ovarii.

Struma ovarii are specialized teratomas consisting of thyroid tissue with various microscopic features, ranging from benign to malignant. We report a rare form of malignant struma ovarii, composed exclusively of a follicular variant of papillary thyroid carcinoma with capsular invasion, which occurred in a 65-yr-old woman.

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A Hormonally Active Malignant Struma Ovarii

Struma ovarii is a rare monodermal variant of ovarian teratoma that contains at least 50% thyroid tissue. Less than 8% of struma ovarii cases present with clinical and biochemical evidence of thyrotoxicosis due to ectopic production of thyroid hormone and only 5% undergo malignant transformation into a papillary thyroid carcinoma. Only isolated cases of hormonally active papillary thyroid carci...

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Malignant Struma Ovarii: A Case Report

We present a case of a 40-yr-old woman diagnosed with a primary malignant struma ovarii. The patient was admitted with the complaint of pelvic pain and a large pelvic mass in the mid-portion of lower abdomen on gynecological examination. Pre-operative tumor markers and routine biochemistry were unremarkable. She was treated with total abdominal hysterectomy and right salpingo-oopherectomy. Post...

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Pregnancy following treated malignant struma ovarii.

Struma ovarii [SO] is a rare, highly specialised form of mature ovarian teratoma, consisting predominantly of thyroid tissue. Malignant transformation occurs in about 5% of SO [1]. Diagnosis of malignant SO is usually made histologically. The majority of malignant SO show a follicular or papillary pattern of thyroid carcinoma. Conservative ovarian surgery is preferred when there is a concern ab...

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An unusual variant of malignant struma ovarii.

Struma ovarii is a highly specialised form of mature ovarian teratoma. When thyroid tissue constitutes 50% or more of the ovarian neoplasm, the tumour is termed struma ovarii. Malignant struma ovarii is rare and makes up 0.1-0.3% of all ovarian teratomas [2]. We describe a case of follicular variant of papillary carcinoma arising from struma ovarii with elevated CA-125 and pseudo-Meig syndrome.

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ژورنال

عنوان ژورنال: Endocrine Abstracts

سال: 2016

ISSN: 1479-6848

DOI: 10.1530/endoabs.41.ep353